Google Scholar Citations / ORCID / Kathrin Breuker

66) H. Glasner, C. Riml, R. Micura, K. Breuker: Label-free, direct localization and relative quantitation of the RNA nucleobase methylations m6A, m5C, m3U, and m5U by top-down mass spectrometry, accepted for publication in Nucleic Acids Res. OPEN ACCESS ARTICLE

65) E.M. Schneeberger, K. Breuker: Native top-down mass spectrometry of TAR RNA in complex with a wild-Type tat peptide for binding site mapping, Angew. Chem. 129, 1274-1278 (2017); Angew. Chem. Int. Ed. 56, 1254-1258 (2017) OPEN ACCESS ARTICLE

64) M. Schennach, E.M. Schneeberger, K. Breuker: Unfolding and folding of the three-helix bundle protein KIX in the absence of solvent, J. Am. Soc. Mass Spectrom. 27, 1079-1088 (2016) OPEN ACCESS ARTICLE

63) A.I. Cabedo Martinez, K. Weinhäupl, W.K. Lee, N.A. Wolff, B. Storch, S. Żerko, R. Konrat, W. Koźmiński, K. Breuker, F. Thévenod, N. Coudevylle: Biochemical and structural characterization of the interaction between the Siderocalin NGAL/LCN2 and the N-terminal domain of its endocytic receptor SLC22A17, J. Biol. Chem. 291, 2917-2930 (2016) OPEN ACCESS ARTICLE

62) T.P. Hoernes, N. Clementi, K. Faserl, H. Glasner, K. Breuker, H. Lindner, A. Hüttenhofer, M. Erlacher: Nucleotide modifications within bacterial messenger RNAs regulate their translation and are able to rewire the genetic code, Nucleic Acids Res. 44, 852-862 (2016) OPEN ACCESS ARTICLE

61) A.G. Flamm, A.L. Le Roux, B.M. López, B. Storch, K. Breuker, R. Konrat, M. Pons, N. Coudevylle: N-lauroylation during the expression of recombinant N-myristoylated proteins. Implications and solutions, ChemBioChem, 17, 82-89 (2016) OPEN ACCESS ARTICLE

60) M. Kosutic, S. Neuner, A. Ren, S. Flür, C. Wunderlich, E. Mairhofer, N. Vusurovic, J. Seikowski, K. Breuker, C. Höbartner, D.J. Patel, C. Kreutz, R. Micura: A mini-twister variant and residues/cations impacting on the phosphodiester cleavage chemistry of this ribozyme class, Angew. Chem. 127, 15343-15348 (2015); Angew. Chem. Int. Ed. 54, 15128-15133 (2015)

59) C. Riml, H. Glasner, M.T. Rodgers, R. Micura, K. Breuker: On the mechanism of RNA phosphodiester backbone cleavage in the absence of solvent, Nucleic Acids Res. 43, 5171-5181 (2015) OPEN ACCESS ARTICLE

58) M. Schennach, K. Breuker: Probing protein structure and folding in the gas phase by electron capture dissociation, J. Am. Soc. Mass Spectrom. 26, 1059-1067 (2015) OPEN ACCESS ARTICLE

57) K. Breuker: Characterization of ribonucleic acids and their modifications by Fourier transform ion cyclotron resonance mass spectrometry, book chapter in "Nucleic Acids in the Gas Phase" (Physical Chemistry in Action 2014), edited by Valérie Gabelica, pp 185-202, Springer Berlin Heidelberg (August 2014)

56) K. Breuker: Structure Characterization of Biomolecules (Editorial) ChemistryOpen 3, 137 (2014) OPEN ACCESS ARTICLE

55) M. Hartl, S. Glasauer, T. Valovka, K. Breuker, B. Hobmayer, K. Bister: Hydra myc2, a unique pre-bilaterian member of the myc gene family, is activated in cell proliferation and gametogenesis Biology Open 3, 397-407 (2014) OPEN ACCESS ARTICLE

54) M. Schennach, K. Breuker: Proteins with highly similar native folds can show vastly dissimilar folding behavior when desolvated Angew. Chem. 126, 168-172 (2014); Angew. Chem. Int. Ed. 53, 164-168 (2014) OPEN ACCESS ARTICLE

53) T. Valovka, M. Schönfeld, P. Raffeiner, K. Breuker, T. Dunzendorfer-Matt, M. Hartl, K. Bister: Transcriptional control of DNA replication licensing by Myc Sci. Rep. 3, Article number: 3444 (2013) OPEN ACCESS ARTICLE

52) R. Micura, C. Kreutz, K. Breuker: A personal perspective on chemistry-driven RNA research Biopolymers 99, 1114-1123 (2013)

51) O.S. Skinner, K. Breuker, F.W. McLafferty: Charge site mass spectra: Conformation-sensitive components of the electron capture dissociation spectrum of a protein J. Am. Soc. Mass Spectrom. 24, 807-810 (2013)

50) B. Ganisl, K. Breuker: Does electron capture dissociation cleave protein disulfide bonds? ChemistryOpen 1, 260-268 (2012) OPEN ACCESS ARTICLE

49) M. Taucher, K. Breuker: Characterization of modified RNA by top-down mass spectrometry Angew. Chem. 124, 11451-11454 (2012); Angew. Chem. Int. Ed. 51, 11289-11292 (2012) OPEN ACCESS ARTICLE

48) O.S. Skinner, F.W. McLafferty, K. Breuker: How Ubiquitin unfolds after transfer into the gas phase J. Am. Soc. Mass Spectrom. 23, 1011-1014 (2012) OPEN ACCESS ARTICLE

47) K. Breuker, O.S. Skinner, F.W. McLafferty: Femtosecond laser vaporization that preserves protein-folded structure: an unproven idea Proc. Natl. Acad. Sci. USA 109, E206 (2012) OPEN ACCESS ARTICLE

46) B. Ganisl, M. Taucher, C. Riml, K. Breuker: Charge as you like! Efficient manipulation of negative ion net charge in electrospray ionization of proteins and nucleic acids Eur. J. Mass Spectrom. 17, 333-343 (2011) OPEN ACCESS ARTICLE

45) B. Ganisl, T. Valovka, M. Hartl, M. Taucher, K. Bister, K. Breuker: Electron detachment dissociation for top-down mass spectrometry of acidic proteins Chem. Eur. J. 17, 4460-4469 (2011) OPEN ACCESS ARTICLE

44) K. Breuker, S. Brüschweiler, M. Tollinger: Electrostatic stabilization of a native protein structure in the gas phase Angew. Chem. 123, 903-907 (2011); Angew. Chem. Int. Ed. 50, 873-877 (2011) OPEN ACCESS ARTICLE

43) M. Taucher, B. Ganisl, K. Breuker: Identification, localization, and relative quantitation of pseudouridine in RNA by tandem mass spectrometry of hydrolysis products Int. J. Mass Spectrom. 304, 91-97 (2011) OPEN ACCESS ARTICLE

42) M. Taucher, K. Breuker: Top-down mass spectrometry for sequencing of larger (up to 61 nt) RNA by CAD and EDD J. Am. Soc. Mass Spectrom. 21, 918-929 (2010) OPEN ACCESS ARTICLE

41) M. Hartl, A.M. Mitterstiller, T. Valovka, K. Breuker, B. Hobmayer, K. Bister: Stem cell-specific activation of an ancestral myc protooncogene with conserved basic functions in the early metazoan Hydra Proc. Natl. Acad. Sci. USA 107, 4051-4056 (2010) OPEN ACCESS ARTICLE

40) M. Taucher, U. Rieder, K. Breuker: Minimizing base loss and internal fragmentation in collisionally activated dissociation of multiply deprotonated RNA J. Am. Soc. Mass Spectrom. 21, 278-285 (2010) OPEN ACCESS ARTICLE

39) F.W. McLafferty, S. Castro, K. Breuker: Multi-step evolution of protein conformation on electrospray into the gas phase Eur. J. Mass Spectrom. 16, 437-442 (2010)

38) X. Kong, C. Lin, G. Infusini, H.B. Oh, H. Jiang, K. Breuker, C.C. Wu, O.P. Charkin, H.C. Chang, F.W. McLafferty: Numerous isomers of serine octamer ions characterized by infrared photodissociation spectroscopy ChemPhysChem 10, 2603-2606 (2009)

37) K. Breuker, F.W. McLafferty: Stepwise evolution of native protein structure with electrospray into the gas phase, 10-12 to 102 s Proc. Natl. Acad. Sci. USA 105, 18145-18152 (2008) OPEN ACCESS ARTICLE

36) M.Z. Steinberg, R. Elber, F.W. McLafferty, R.B. Gerber, K. Breuker: Early structural evolution of native Cytochrome c after solvent removal ChemBioChem 9, 2417-2423 (2008)

35) K. Breuker, M. Jin, X. Han, H. Jiang, F.W. McLafferty: Top-down identification and characterization of biomolecules by mass spectrometry J. Am. Soc. Mass Spectrom. 19, 1045-1053 (2008) OPEN ACCESS ARTICLE

34) F.W. McLafferty, K. Breuker, M. Jin, X. Han, G. Infusini, H. Jiang, X. Kong, T.P. Begley: Top-down mass spectrometry, a powerful complement to the high capabilities of proteolysis proteomics FEBS J. 274, 6256-6268 (2007) OPEN ACCESS ARTICLE

33) M.Z. Steinberg, K. Breuker, R. Elber, R.B. Gerber: The dynamics of water evaporation from partially solvated Cytochrome c in the gas phase Phys. Chem. Chem. Phys. 9, 4690-4697 (2007)

32) X. Han, M. Jin, K. Breuker, F.W. McLafferty: Extending top-down mass spectrometry to proteins with masses greater than 200 kilodaltons Science 314, 109-112 (2006)

31) K. Breuker: Protein structure and folding in the gas phase: Ubiquitin and Cytochrome c. book chapter no. 5 in "Principles of mass spectrometry applied to biomolecules" edited by Chava Lifshitz and Julia Laskin, John Wiley & Sons, Inc. (October 2006)

30) K. Breuker: Segmental charge distributions of Cytochrome c on transfer into the gas phase Int. J. Mass Spectrom. 253, 249-255 (2006)

29) H. Zhai, X. Han, K. Breuker, F.W. McLafferty: Consecutive ion activation for top down mass spectrometry: Improved protein sequencing by nozzle skimmer dissociation Anal. Chem. 77, 5777-5784 (2005)

28) K. Breuker, F.W. McLafferty: The thermal unfolding of native Cytochrome c in the transition from solution to gas phase probed by native electron capture dissociation Angew. Chem. 117, 4989-4992 (2005); Angew. Chem. Int. Ed. 44, 4911-4914 (2005)

27) H.-B. Oh, C. Ling, H.Y. Hwang, H. Zhai, K. Breuker, V. Zabrouskov, B.K. Carpenter, F.W. McLafferty: Infrared photodissociation spectroscopy of electrosprayed ions in a Fourier transform mass spectrometer J. Am. Chem. Soc. 127, 4076-4083 (2005)

26) K. Breuker: The study of protein-ligand interactions by mass spectrometry - a personal view Int. J. Mass Spectrom. 239, 33-41 (2004)

25) K. Breuker, H.-B. Oh, C. Ling, B.K. Carpenter, F.W. McLafferty: Nonergodic and conformational control of the electron capture dissociation of protein cations Proc. Natl. Acad. Sci. USA 101, 14011-14016 (2004) OPEN ACCESS ARTICLE

24) C. Höbartner, H. Mittendorfer, K. Breuker, R. Micura: Triggering of RNA secondary structure by a functionalized nucleobase Angew. Chem. 116, 4012-4015 (2004); Angew. Chem. Int. Ed. 43, 3922-3925 (2004)

23) M. Narayan, G. Xu, D.R. Ripoll, H. Zhai, K. Breuker, C. Wanjalla, H.J. Leung, A. Navon, E. Welker, F.W. McLafferty, H.A. Scheraga: Dissimilarity in the reductive unfolding pathways of two ribonuclease homologues J. Mol. Biol. 338, 795-809 (2004)

22) K. Breuker: New mass spectrometric methods for the quantification of protein-ligand binding in solution Angew. Chem. 116, 22-25 (2004); Angew. Chem. Int. Ed. 43, 22-25 (2004)

21) K. Breuker, F.W. McLafferty: Native electron capture dissociation for the structural characterization of noncovalent interactions in native Cytochrome c Angew. Chem. 115, 5048-5052 (2003); Angew. Chem. Int. Ed. 42, 4900-4904 (2003)

20) M. Oberhuber, J. Berghold, K. Breuker, S. Hörtensteiner, B. Kräutler: Breakdown of chlorophyll: A nonenzymatic reaction accounts for the formation of the colorless "nonfluorescent" chlorophyll catabolites Proc. Natl. Acad. Sci. USA 100, 6910-6915 (2003) OPEN ACCESS ARTICLE

19) K. Breuker, R. Knochenmuss, A. Stortelder, J. Zhang, R. Zenobi: Thermodynamic control of final ion distributions in MALDI: in-plume proton transfer reactions Int. J. Mass Spectrom. 226, 211-222 (2003)

18) H.-B. Oh, K. Breuker, S.-K. Sze, Y. Ge, B.K. Carpenter, F.W. McLafferty: Secondary and tertiary structures of gaseous protein ions characterized by electron capture dissociation mass spectrometry and photofragment spectroscopy Proc. Natl. Acad. Sci. USA 99, 15863-15868 (2002) OPEN ACCESS ARTICLE

17) J. Berghold, K. Breuker, M. Oberhuber, S. Hörtensteiner, B. Kräutler: Chlorophyll breakdown in spinach: on the structure of five nonfluorescent chlorophyll catabolites Photosynth. Res. 74, 109-119 (2002)

16) K. Breuker, H.-B. Oh, D.M. Horn, B.A. Cerda, F.W. McLafferty: Hydrogen atom loss in electron capture dissociation: A FT-ICR study with single isotopomeric ubiquitin ions Eur. J. Mass Spectrom. 8, 177-180 (2002) OPEN ACCESS ARTICLE

15) K. Breuker, H.-B. Oh, D.M. Horn, B.A. Cerda, F.W. McLafferty: Detailed unfolding and folding of gaseous ubiquitin ions characterized by electron capture dissociation J. Am. Chem. Soc. 124, 6407-6420 (2002)

14) B.A. Cerda, D.M. Horn, K. Breuker, F.W. McLafferty: Sequencing of specific copolymer oligomers by electron capture dissociation mass spectrometry J. Am. Chem. Soc. 124, 9287-9291 (2002)

13) D.M. Horn, K. Breuker, A.J. Frank, F.W. McLafferty: Kinetic intermediates in the folding of gaseous protein ions characterized by electron capture dissociation J. Am. Chem. Soc. 123, 9792-9799 (2001)

12) B.A. Cerda, K. Breuker, D.M. Horn, F.W. McLafferty: Charge/radical site initiation versus Coulombic repulsion for cleavage of multiply charged ions. Charge solvation in poly(alkene glycol) ions J. Am. Soc. Mass Spectrom. 12, 565-570 (2001) OPEN ACCESS ARTICLE

11) F.W. McLafferty, D.M. Horn, K. Breuker, Y. Ge, M.A. Lewis, B. Cerda, R.A. Zubarev, B.K. Carpenter: Electron capture dissociation of gaseous multiply charged ions by Fourier-transform ion cyclotron resonance J. Am. Soc. Mass Spectrom. 12, 245-249 (2001) OPEN ACCESS ARTICLE

10) R. Knochenmuss, A. Stortelder, K. Breuker, R. Zenobi: Secondary ion-molecule reactions in matrix-assisted laser desorption/ionization J. Mass Spectrom. 35, 1237-1245 (2000)

9) E. Stevenson, K. Breuker, R. Zenobi: Internal energies of analyte ions generated from different matrix-assisted laser desorption/ionization matrices J. Mass Spectrom. 35, 1035-1041 (2000)

8) B.A. Cerda, D.M. Horn, K. Breuker, B.K. Carpenter, F.W. McLafferty: Electron capture dissociation of multiply-charged oxygenated cations. A nonergodic process Eur. J. Mass Spectrom. 5, 335-338 (1999) OPEN ACCESS ARTICLE

7) K. Breuker, R. Knochenmuss, R. Zenobi: Proton transfer reactions of MALDI matrix monomers and dimers J. Am. Soc. Mass Spectrom. 10, 1111-1123 (1999) OPEN ACCESS ARTICLE

6) U. Baumann, M. Benz, E. Pletscher, M. Siegfried, K. Breuker, R. Zenobi: Biodegradation of sugar alcohol ethoxylates Tenside, Surfactants, Deterg. 36, 288-293 (1999)

5) K. Breuker, R. Knochenmuss, R. Zenobi: The gas-phase basicities of deprotonated MALDI matrix molecules Int. J. Mass Spectrom. 184, 25-38 (1999)

4) K. Breuker, R. Knochenmuss, R. Zenobi: Matrix-assisted laser desorption/chemical ionization with reagent ion generation directly from a liquid matrix Int. J. Mass Spectrom. 176, 149-159 (1998), Best Student Paper Award 1999 for the best paper on technique development.

3) R. Knochenmuss, V. Karbach, U. Wiesli, K. Breuker, R. Zenobi: The matrix suppression effect in matrix-assisted laser desorption/ionization: Application to negative ions and further characteristics Rapid Commun. Mass Spectrom. 12, 529-534 (1998)

2) R.J.J.M. Steenvoorden, K. Breuker, R. Zenobi: The gas-phase basicities of matrix-assisted laser desorption/ionization matrices Eur. J. Mass Spectrom. 3, 339-346 (1997) OPEN ACCESS ARTICLE

1) F. Dubois, R. Knochenmuss, R.J.J.M. Steenvoorden, K. Breuker, R. Zenobi: On the mechanism and control of salt-induced resolution loss in matrix-assisted laser desorption/ionization Eur. J. Mass Spectrom. 2, 167-172 (1996) OPEN ACCESS ARTICLE